The Fibrinogen test measures the level of fibrinogen, a key protein involved in the blood clotting process, in the plasma. Fibrinogen is produced by the liver and is converted into fibrin during the final stages of blood clot formation, creating the structural framework of a clot. This test is typically used to evaluate bleeding or abnormal clotting disorders, such as liver disease, disseminated intravascular coagulation (DIC), or congenital fibrinogen deficiency. Low fibrinogen levels may indicate excessive consumption in conditions like severe bleeding, DIC, or liver failure, while high levels can be associated with acute inflammation, infections, pregnancy, or autoimmune diseases. Fibrinogen is also known as an acute-phase reactant, meaning its levels increase in inflammatory conditions. The test is often performed alongside other coagulation tests such as PT, PTT, and platelet count to help determine the cause of coagulation disorders. Its results are important in preoperative patient management, monitoring anticoagulant therapies, or diagnosing underlying diseases.

